Violacein: properties and biological activities.
نویسندگان
چکیده
The violet pigment violacein is an indole derivative, isolated mainly from bacteria of the genus Chromobacterium, which exhibits important antitumoral, antimicrobial and antiparasitary properties. Furthermore, the formulation of violacein in different polymeric carriers developed so far offers alternative approaches to overcoming physiological barriers and undesirable physicochemical properties in vivo, thus improving its efficacy.
منابع مشابه
Violacein: Properties and Production of a Versatile Bacterial Pigment
Violacein-producing bacteria, with their striking purple hues, have undoubtedly piqued the curiosity of scientists since their first discovery. The bisindole violacein is formed by the condensation of two tryptophan molecules through the action of five proteins. The genes required for its production, vioABCDE, and the regulatory mechanisms employed have been studied within a small number of vio...
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The purple-coloured pigment violacein, produced mainly by bacteria of the genus Chromobacterium, had attracted and increased interest owing to its important biological activities and pharmacological potential. In the present study experiments were designed to investigate the effect of different fermentation conditions on the violacein production by novel isolate Chromobacterium vaccinii CV5. Di...
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Natural products are an inexhaustible source of compounds with promising pharmacological activities including antiviral action. Violacein, the major pigment produced by Chromobacterium violaceum, has been shown to have antibiotic, antitumoral and anti-Trypanosoma cruzi activities. The goal of the present work was to evaluate the cytotoxicity of violacein and also its potential antiviral propert...
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ورودعنوان ژورنال:
- Biotechnology and applied biochemistry
دوره 48 Pt 3 شماره
صفحات -
تاریخ انتشار 2007